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. 2017 Dec 7;7:17126. doi: 10.1038/s41598-017-17067-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in lymphocyte subsets and circulating cytokines after acute ZIKV infection. (A) Polychromatic flow cytometry was used to identify T cells (upper left), CD8 T cells (upper right), NKG2A + NK cells (lower left), and CD20 + B cells expressing activation markers CD86 and HLA-DR (lower right). (B) Increases in protein expression of interferon-gamma (IFN-γ) and monokine induced by IFN-γ (MIG) were detected using a Luminex assay.