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. 2017 Dec 7;10:58. doi: 10.1186/s13072-017-0165-x

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Naked DNA correction promotes standardization of fragile nucleosomes. a The metagene analysis of nucleosomal occupancy in 1856 genes that contained a fragile − 1 nucleosome, according to [17]. Genes were scaled to the same length and then aligned to their TSS. The purple arrow indicates the expected position of fragile nucleosomes. b The metagene analysis of nucleosomal occupancy in 2872 genes that contained a stable − 1 nucleosome, according to [17]. c The metagene analysis of nucleosomal occupancy in RP genes. d A comparison of the effect of the naked DNA correction on the detection of histone and non-histone MNase-sensitive particles, according to the data from [43]