TABLE I. Analysis of sequenced peptides for symptomatic sera.
| # Spot | Plasmo DB access | Description | Peptides | Unique peptides | PSM | MW(kDa) calculated/observed | pI calculated/observed |
|---|---|---|---|---|---|---|---|
| 1 | PF3D7_0533100 | organism=Plasmodium_falciparum_3D7 | product=erythrocyte membrane protein 1 (PfEMP1), truncated (VAR1CSA) | KScVMcMQK | 1 | 1 | 367.7/260 | 8.37/4.0 |
| 2 | PfIT_11_v2-1-184488-188775/PF3D7_0611800 | organism=Plasmodium_falciparum_3D7 | product=conserved Plasmodium protein, unknown function | LGHKKLSmIR | 1 | 24 | 12/40 | 9.82/4.0 |
| 3 | PF3D7_1029600 | organism=Plasmodium_falciparum_3D7 | product=adenosine deaminase, putative | MNLWAVQK VSESQEIDLVK | 2 | 3 | 42.4/40 | 5.69/5.0 |
| 4 | PF3D7_1110900 | organism=Plasmodium_falciparum_3D7 | product=ES2 protein, putative | TSLSVVENKKNEK | 1 | 3 | 69/30 | 9.22/5.0 |
| 5 | PfIT_04_v2-3-302028-302201/PF3D7_1356500 | organism=Plasmodium_falciparum_3D7 | product=conserved Plasmodium protein, unknown function | IEVTILmcLVK | 1 | 26 | 7.1/35 | 9.06/3.0 |
Proteins and peptides recognised by symptomatic natural antibodies and sequenced by LC-MS/MS. PSM: peptide sequence matching; MW: molecular weight; pI: isoelectric point.