Box 2. Summary of adolescent‐specific 2016 WHO recommendations
1. When to start ART in adolescents:	ART should be initiated in all adolescents living with HIV regardless of WHO clinical stage and at any CD4 count. [conditional recommendation, low‐quality evidence] As a priority ART should be initiated in all adolescents with severe or advanced HIV clinical disease (WHO clinical stage 3 or 4) and adolescents with a CD4 count ≤ 350 cells/mm3. [strong recommendation, moderate‐quality evidence]
2. First‐line ART for adolescents:	First‐line ART for adolescents should consist of two nucleoside reverse transcriptase inhibitors and a non‐nucleoside reverse transcriptase inhibitor or an integrase inhibitor. [strong recommendation, low‐quality evidence] TDF + 3TC (or FTC) + EFV as a fixed‐dose combination is recommended as the preferred option to initiate ART [strong recommendation, low‐quality evidence] TDF + 3TC (or FTC) + DTG or TDF + 3TC (or FTC) + EFV400 may be used as alternative options to initiate ART [conditional recommendation, low quality evidence]
3. Adolescent‐friendly health services:	Adolescent‐friendly health services should be implemented in HIV services to ensure engagement and improved outcomes [strong recommendation, low‐quality evidence]