Table 3.
Changes of plaque composition in relative and absolute values
| DM (17 pts, 192 segments) | non-DM (44 pts, 506 segments) | p | |
|---|---|---|---|
| Fibrous tissue BL % | 0.55 ± 0.15 | 0.55 ± 0.19 | 0.69 |
| Fibrous tissue FU % | 0.57 ± 0.12 | 0.56 ± 0.19 | 0.7 |
| Δ Fibrous tissue % | 0.03 ± 0.14 | 0.01 ± 0.14 | 0.32 |
| p value for change between BL and FU | 0.02 | 0.78 | |
| Fibrous tissue BL (mm2) | 1.80 ± 1.31 | 2.01 ± 1.41 | 0.26 |
| Fibrous tissue FU (mm2) | 2.00 ± 1.51 | 1.89 ± 1.41 | 0.92 |
| Δ Fibrous tissue (mm2) | 0.21 ± 0.75 | − 0.12 ± 0.60 | 0.001 |
| p value for change between BL and FU | 0.037 | 0.05 | |
| Fibrous-fatty tissue BL % | 0.15 ± 0.12 | 0.14 ± 0.11 | 0.81 |
| Fibrous-fatty tissue FU % | 0.15 ± 0.08 | 0.14 ± 0.11 | 0.84 |
| Δ Fibrous-fatty tissue % | 0.0 ± 0.13 | 0.0 ± 0.12 | 0.71 |
| p value for change between BL and FU | 0.83 | 0.42 | |
| Fibrous-fatty tissue BL (mm2) | 0.41 ± 0.45 | 0.52 ± 0.55 | 0.12 |
| Fibrous-fatty tissue FU (mm2) | 0.56 ± 0.62 | 0.51 ± 0.58 | 0.86 |
| Δ Fibrous-fatty tissue (mm2) | 0.15 ± 0.50 | − 0.00 ± 0.49 | 0.17 |
| p value for change between BL and FU | 0.002 | 0.87 | |
| NC BL % | 0.18 ± 0.12 | 0.15 ± 0.15 | 0.43 |
| NC FU % | 0.16 ± 0.07 | 0.14 ± 0.09 | 0.17 |
| Δ NC % | − 0.02 ± 0.12 | − 0.02 ± 0.1 | 0.94 |
| p value for change between BL and FU | 0.03 | 0.003 | |
| NC BL (mm2) | 0.83 ± 1.02 | 0.68 ± 0.86 | 0.66 |
| NC FU (mm2) | 0.63 ± 0.55 | 0.53 ± 0.59 | 0.51 |
| Δ NC (mm2) | − 0.20 ± 0.65 | −0.15 ± 0.49 | 0.9 |
| p value for change between BL and FU | 0.001 | < 0.001 | |
| NC abutting lumen BL (°) | 61.36 ± 58.65 | 54.32 ± 57.43 | 0.75 |
| NC abutting lumen FU (°) | 62.63 ± 53.89 | 51.05 ± 51.02 | 0.26 |
| Δ NC abutting lumen (°) | 1.27 ± 50.23 | − 3.27 ± 41.79 | 0.41 |
| p value for change between BL and FU | 0.79 | 0.24 | |
| DC BL % | 0.1 ± 0.09 | 0.08 ± 0.09 | 0.26 |
| DC FU % | 0.09 ± 0.07 | 0.08 ± 0.08 | 0.11 |
| Δ DC % | 0.0 ± 0.09 | 0.0 ± 0.07 | 0.93 |
| p value for change between BL and FU | 0.95 | 0.99 | |
| DC BL (mm2) | 0.43 ± 0.55 | 0.33 ± 0.50 | 0.37 |
| DC FU (mm2) | 0.37 ± 0.39 | 0.29 ± 0.40 | 0.26 |
| Δ DC (mm2) | −0.06 ± 0.34 | − 0.04 ± 0.24 | 0.82 |
| p value for change between BL and FU | 0.1 | 0.06 |
We found higher LAPS at follow-up in diabetics compared to non-diabetics (0.13 ± 1.89 vs. − 0.38 ± 1.8, p = 0.002). DM patients also experienced an increase of LAPS during the study, unlike non-DM patients for which LAPS decreased (0.13 ± 1.79 vs. − 0.23 ± 1.66, p = 0.018)
Italic values indicate significant differences