Table 1.
Characteristics comparison between participants with and without OSA
| Variables | Without OSA (n = 222) | OSA (n = 162) |
|---|---|---|
| Age (years) | 47 ± 12 | 53 ± 15* |
| Male, n (%) | 140 (63.1) | 106 (65.4) |
| BMI (kg/m2) | 23.3 ± 5.5 | 27.8 ± 6.8* |
| Current smoking, n (%) | 78 (35.1) | 78 (48.1)# |
| Clinic-SBP (mm Hg) | 139 ± 15 | 143 ± 18* |
| Clinic-DBP (mm Hg) | 85 ± 9 | 86 ± 10 |
| Clinic-HR (bpm) | 75 ± 10 | 79 ± 12 |
| FPG (mmol/L) | 5.6 ± 0.4 | 5.5 ± 0.6 |
| TC (mmol/L) | 5.0 ± 0.7 | 5.2 ± 0.5 |
| TG (mmol/L) | 1.8 ± 0.6 | 1.9 ± 0.8 |
| HDL-C (mmol/L) | 1.0 ± 0.4 | 1.1 ± 0.4 |
| LDL-C (mmol/L) | 3.2 ± 0.4 | 3.4 ± 0.6 |
| Cr (umol/L) | 74.9 ± 12.8 | 71.8 ± 13.6 |
| Hs-CRP (mg/dL) | 7.2 ± 3.6 | 9.7 ± 4.8* |
| AHI (events/h) | 3.4 ± 1.4 | 11.6 ± 6.2# |
| CVD, n (%) | 79 (35.6) | 66 (40.7)* |
| Anti-platelet agent, n (%) | 98 (44.1) | 68 (42.0) |
| Statins, n (%) | 79 (35.6) | 59 (36.4) |
| ACEI/ARB, n (%) | 160 (72.1) | 119 (73.5) |
| CCB, n (%) | 42 (18.9) | 33 (20.4) |
| Diuretic, n (%) | 70 (31.5) | 52 (32.1) |
| Beta-blocker, n (%) | 43 (19.4) | 37 (22.8) |
| Alpha-blocker, n (%) | 12 (5.4) | 10 (6.2) |
| Anti-HTN medications number | 1.7 ± 0.5 | 2.5 ± 0.8* |
BMI = body mass index; SBP/DBP = systolic/diastolic blood pressure; HR = heart rate; bpm = beat per minute; FPG = fasting plasma glucose; TC = total cholesterol; TG = triglyceride; HDL-C = high density lipoprotein-cholesterol; LDL-C = low density lipoprotein-cholesterol; Cr = creatinine; Hs-CRP = high sensitivity C-reactive protein; SD = standard deviation; AHI = apnea hypopnea index; OSA = obstructive sleep apnea; CVD = cardiovascular disease; ACEI/ARB = angiotensin converting enzyme inhibitor/angiotensin receptor blocker; CCB = calcium channel blocker; *P < 0.05 and # P < 0.01 vs without OSA group