Table 1. The enriched KEGG pathways for the genes in module 1 and 2 from WGCNA analysis.
| Pathway | # of genes | Q-value* |
|---|---|---|
| Module 1 | ||
| Metabolism | 43 | 6.26E−07 |
| Isoleucine degradation | 3 | 0.04218 |
| Module 2 | ||
| Collagen formation | 14 | 4.54E−12 |
| Extracellular matrix organization | 21 | 4.92E−12 |
| Collagen biosynthesis and modifying enzymes | 13 | 1.54E−11 |
| ECM proteoglycans | 11 | 2.85E−10 |
| Collagen degradation | 10 | 7.38E−09 |
| Assembly of collagen fibrils and other multimeric structures | 9 | 3.76E−08 |
| Degradation of the extracellular matrix | 12 | 5.32E−08 |
| Integrin cell surface interactions | 11 | 2.07E−07 |
| NCAM1 interactions | 6 | 8.55E−06 |
| Glycosaminoglycan metabolism | 9 | 0.00409 |
| MET activates PTK2 signaling | 5 | 0.00967 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | 5 | 0.01919 |
| Non-integrin membrane-ECM interactions | 5 | 0.02361 |
| Axon guidance | 14 | 0.04552 |
Notes.
* Q-values: the raw P-values of the hypergeometric test were corrected by Benjamini–Hochberg multiple testing correction.