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The Scientific World Journal logoLink to The Scientific World Journal
. 2011 Jan 18;11:235–241. doi: 10.1100/tsw.2011.15

Lipoxins: A Novel Regulator in Embryo Implantation

Jing Xiong 1,2, Pan Zeng 2, Duyun Ye 2,*
PMCID: PMC5720083  PMID: 21258764

Abstract

Embryo implantation is essential for mammalian pregnancy, which involves intricate cross-talk between the blastocyst and the maternal endometrium. Recent advances have identified various molecules crucial to implantation and endometrial receptivity, including leukemia inhibitory factor, calcitonin, and homeobox A10. There is a close relationship between implantation and inflammation. Lipoxins, important in the resolution of inflammation, may be a potential regulator in implantation. Here we discuss the hypothesis that lipoxins may work as a novel regulator in embryo implantation and the possible molecular mechanisms.

Keywords: lipoxins, inflammation, implantation


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