Table 3.
Effect of Creatinine Spikes on Survival, Using Data From All Admissions (n = 636 Admissions).
| 30-Day survival % |
90-Day survival % |
|||||||
|---|---|---|---|---|---|---|---|---|
| Cut-off, Peak 48 h—Adm | Peak <1.2 mg/dL | P | Peak 1.2+ mg/dL | P | Peak <1.2 mg/dL | P | Peak 1.2+ mg/dL | P |
| +0.1 mg/dL | 0.52 | <0.01 | 0.71 | 0.01 | ||||
| Less than +0.1 | 95% (193/204) | 90% (168/187) | 87% (173/200) | 80% (142/178) | ||||
| At least +0.1 | 93% (74/80) | 72% (106/148) | 85% (66/78) | 66% (96/146) | ||||
| +0.2 mg/dL | 0.12 | <0.01 | 0.33 | <0.01 | ||||
| Less than +0.2 | 95% (227/239) | 89% (185/208) | 87% (203/234) | 79% (158/199) | ||||
| At least +0.2 | 89% (40/45) | 70% (89/127) | 82% (36/44) | 64% (80/125) | ||||
| +0.3 mg/dL | 0.11 | <0.01 | 0.71 | <0.01 | ||||
| Less than +0.3 | 95% (239/252) | 89% (194/219) | 86% (213/247) | 79% (166/209) | ||||
| At least +0.3 | 88% (28/32) | 69% (80/116) | 84% (26/31) | 63% (72/115) | ||||
| +0.4 mg/dL | 1a | 0.02 | 1a | 0.06 | ||||
| Less than +0.4 | 94% (263/280) | 84% (234/279) | 86% (235/274) | 75% (202/269) | ||||
| At least +0.4 | 100% (4/4) | 71% (40/56) | 100% (4/4) | 65% (36/55) | ||||
| +0.5 mg/dL | 1a | 0.01 | 1a | 0.02 | ||||
| Less than +0.5 | 94% (266/283) | 84% (255/305) | 86% (238/277) | 75% (222/295) | ||||
| At least +0.5 | 100% (1/1) | 63% (19/30) | 100% (1/1) | 55% (16/29) | ||||
Peak 48 h—Adm: peak creatinine within 48 hours of admission, minus admission level.
P-values from GEE, except abinomial exact test.
Of 636 admission, 619 admissions had adequate data and occurred within prescribed time frame for analysis.