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. Author manuscript; available in PMC: 2017 Dec 28.
Published in final edited form as: Chem Rev. 2016 Dec 8;116(24):15035–15088. doi: 10.1021/acs.chemrev.6b00488

Scheme 8.

Scheme 8

Jacobsen’s Synthesis of the Core of Fostriecin Features a Hydrolytic Resolution of a Racemic Epoxide Catalyzed by a Cobalt Complex and a Chromium-Catalyzed Hetero-Diels–Alder Reaction