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. Author manuscript; available in PMC: 2017 Dec 28.
Published in final edited form as: Chem Rev. 2016 Dec 8;116(24):15035–15088. doi: 10.1021/acs.chemrev.6b00488

Scheme 55.

Scheme 55

Hatakeyama’s Synthesis of the Core of Phoslactomycin B Relies on Iterative Horner–Wadsworth–Emmons Olefinations and Installs the Aminoethyl Group via Cross-Coupling