Table 1.
Participant characteristics.
| Variables | NSCLC group (n = 20) mean ± SD | Healthy controls (n = 20) mean ± SD | p Value | ||
|---|---|---|---|---|---|
| Age (year) | 68 ± 10 | 69 ± 5 | 0.67 | ||
| Height (cm) | 165 ± 13 | 167 ± 6 | 0.36 | ||
| Weight (kg) | 72 ± 21 | 71 ± 14 | 0.82 | ||
| BMI (kg m−2) | 26 ± 6 | 25 ± 4 | 0.79 | ||
| Smoking (pack·years) | 35 ± 17 | 0.3 ± 0.9 | <0.001 | ||
| FEV1 (L) | 1.69 ± 0.50 | 2.68 ± 0.54 | <0.001 | ||
| FEV1 (% predicted) | 67 ± 17 | 103 ± 15 | <0.001 | ||
| FVC (L) | 2.74 ± 0.74 | 3.44 ± 0.75 | <0.001 | ||
| FVC (% predicted) | 81 ± 10 | 99 ± 15 | <0.001 | ||
| n | % | n | % | ||
| Gender, male/female | 7/13 | 35/65 | 7/13 | 35/65 | 0.92 |
| Smoking status | |||||
| Current smoker | 1 | 5 | 0 | 0 | 0.34 |
| Ex-smoker | 16 | 80 | 2 | 10 | <0.001 |
| Never smoked | 3 | 15 | 18 | 90 | <0.001 |
| COPD | 11 | 55 | 0 | 0 | <0.001 |
| Other comorbidities | |||||
| Hypertension | 11 | 55 | 2 | 10 | <0.001 |
| Stable ischaemic heart disease | 3 | 15 | 1 | 5 | 0.25 |
| Diabetes Mellitus | 3 | 15 | 1 | 5 | 0.25 |
| Dyslipidaemia | 5 | 25 | 6 | 30 | 0.38 |
| GORD | 3 | 15 | 1 | 5 | 0.39 |
| Hypothyroidism | 2 | 10 | 3 | 15 | 0.62 |
| Type of NSCLC | |||||
| Adenocarcinoma | 14 | 70 | |||
| Squamous cell carcinoma | 5 | 25 | |||
| Large cell carcinoma | 1 | 5 | |||
| NSCLC stage | |||||
| I | 15 | 75 | |||
| II | 3 | 15 | |||
| IIIA | 2 | 10 | |||
| Types of surgery | |||||
| Open | 8 | 40 | |||
| VATS | 12 | 60 | |||
| Adjuvant chemotherapy | 2 | 10 | |||
BMI: body-mass index; COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; GORD: gastro-oesophageal reflux disease; MVV: maximum voluntary ventilation; NSCLC: non-small cell lung cancer; SD: standard deviation; VATS: video-assisted thoracoscopic surgery.