Table 1.
Basic characteristics of patients with COPD and the matched cohort.
| Patients with COPD (n = 46,778) | Matched cohort (n = 46,778) | p value | |||
|---|---|---|---|---|---|
| Characteristics | n | % | n | % | |
| Median age, years (IQR) | 63 (50–74) | 63 (50–74) | 1.000 | ||
| Median follow-up, years (IQR) | 5.50 (2.44–8.75) | 5.64 (2.59–8.82) | <0.001 | ||
| Age, years | |||||
| ≥65 | 24,556 | 52.5 | 24,556 | 52.5 | 1.000 |
| <65 | 22,222 | 47.5 | 22,222 | 47.5 | |
| Sex | |||||
| Male | 25,813 | 55.2 | 25,813 | 55.2 | 1.000 |
| Female | 20,965 | 44.8 | 20,965 | 44.8 | |
| Median Charlson comorbidity index (IQR)a | 2 (1–4) | 2 (1–4) | 1.000 | ||
| 0–1 | 20,925 | 44.7 | 20,925 | 44.7 | 1.000 |
| 2–3 | 14,047 | 30.1 | 14,047 | 30.1 | |
| ≥4 | 11,806 | 25.2 | 11,806 | 25.2 | |
| Charlson comorbiditiesa | |||||
| AIDS | 46 | 0.1 | 46 | 0.1 | 1.000 |
| Cancer | 5522 | 11.8 | 5522 | 11.8 | 1.000 |
| Cerebrovascular disease | 11,444 | 24.5 | 11,443 | 24.5 | 0.994 |
| Congestive heart failure | 6590 | 14.1 | 6587 | 14.1 | 0.978 |
| Dementia | 2495 | 5.3 | 2496 | 5.3 | 0.988 |
| Diabetes with end-organ damage | 3557 | 7.6 | 3557 | 7.6 | 1.000 |
| Diabetes without end-organ damage | 12,640 | 27.0 | 12,641 | 27.0 | 0.994 |
| Metastatic cancer | 760 | 1.6 | 760 | 1.6 | 1.000 |
| Myocardial infarction | 1688 | 3.6 | 1688 | 3.6 | 1.000 |
| Peptic ulcer disease | 22,842 | 48.8 | 22,845 | 48.8 | 0.984 |
| Peripheral vascular disease | 1986 | 4.2 | 1984 | 4.2 | 0.974 |
| Hemiplegia or paraplegia | 1678 | 3.6 | 1678 | 3.6 | 1.000 |
| Kidney disease | 5952 | 12.7 | 5954 | 12.7 | 0.984 |
| Connective tissue disease | 2858 | 6.1 | 2858 | 6.1 | 1.000 |
| Severe liver disease | 397 | 0.8 | 397 | 0.8 | 1.000 |
IQR: interquartile range; AIDS: acquired immunodeficiency syndrome; COPD: chronic obstructive pulmonary disease.
aChronic lung disease was exempted from scoring.