Table 3.

Factors associated with roflumilast discontinuation (multi variate analysis)

Risk factor	OR	95% CI	p-value
Model A
Age	1.006	0.966–1.047	0.778
BMI (per 1-unit decrease)	1.165	1.046–1.298	0.006
Sex (female)	0.659	0.191–2.277	0.510
% of predicted post-bronchodilator FEV1	0.993	0.970–1.016	0.540
Model B
Age	1.006	0.966–1.047	0.789
BMI <23 kg/m2	2.960	1.410–6.215	0.004
Sex (female)	0.566	0.163–1.964	0.370
% of predicted post-bronchodilator FEV1	0.996	0.973–1.020	0.755

Notes: Model A is the result of analyzing BMI as a continuous variable. Model B is the result of analyzing BMI as a nominal variable.

Abbreviations: BMI, body mass index; FEV₁, forced expiratory volume in 1 second; OR, odds ratio.