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Comparison of LOHHLA and ASCAT, Related to Figure 1
(A) Plot illustrating comparison of ASCAT major copy number and LOHHLA major copy number.
(B and C) Summary of concordant and discordant tumor regions in terms of allelic imbalance (B) and LOH (C).
(D) Schematic illustrating how ASCAT cannot directly infer HLA copy number or which HLA allele is subject to loss. By contrast, LOHHLA uses SNPs covering HLA genes to directly infer HLA copy number.
