Table 4. Multivariate linear regression models of the associations between metabolite levels and memory function.
| Variables | AVLT-immediate recall | AVLT-delayed recall | AVLT-delayed recognition | CFT-immediate recall | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coeff | SD | p value | Coeff | SD | p value | Coeff | SD | p value | Coeff | SD | p value | |
| PTSD | ||||||||||||
| NAA, hippocampus | - | - | - | -0.083 | 0.464 | 0.859 | - | - | - | 0.164 | 0.378 | 0.668 |
| Cr, ACC | -0.011 | 0.466 | 0.959 | - | - | - | 0.231 | 0.504 | 0.652 | - | - | - |
| Age | -0.129 | 0.095 | 0.556 | -0.073 | 0.061 | 0.243 | -0.057 | 0.103 | 0.587 | 0.016 | 0.050 | 0.756 |
| BDI | -0.349 | 0.054 | 0.130 | -0.049 | 0.040 | 0.230 | -0.053 | 0.058 | 0.368 | -0.041 | 0.032 | 0.216 |
| Partial R2 | 0.017 | -0.005 | -0.058 | -0.043 | ||||||||
| p value (model) | 0.364 | 0.429 | 0.626 | 0.601 | ||||||||
| non-PTSD | ||||||||||||
| NAA, hippocampus | - | - | - | -1.744 | 0.608 | 0.011 | - | - | - | -1.420 | 0.897 | 0.132 |
| Cr, ACC | -0.564 | 0.409 | 0.191 | - | - | - | -1.114 | 0.59 | 0.082 | - | - | - |
| Age | -0.076 | 0.041 | 0.086 | -0.04 | 0.051 | 0.439 | -0.124 | 0.059 | 0.056 | 0.003 | 0.075 | 0.969 |
| BDI | -0.027 | 0.037 | 0.472 | -0.065 | 0.043 | 0.153 | 0.024 | 0.053 | 0.664 | -0.069 | 0.064 | 0.297 |
| Partial R2 | 0.267 | 0.410 | 0.362 | 0.057 | ||||||||
| p value (model) | 0.073 | 0.007 | 0.032 | 0.275 | ||||||||
Abbreviations: AVLT, Auditory Verbal Learning Test; CFT, Complex Figure Test; Coeff, coefficient; SD, standard deviation; NAA, N-Acetylaspartate; ACC, Anterior Cingulate Cortex; Cr, Creatine; BDI, Beck Depression Inventory