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. 2017 Dec 7;12(12):e0187449. doi: 10.1371/journal.pone.0187449

Table 4. Summary of marker expression in healthy, abnormal and diseased epithelium.

Marker expression used to classify normal tissue (NT), fibroepithelial polyp (FEP), low-grade dysplasia (LGD), high-grade dysplasia (HGD), T1 OSCC and T4 OSCC.

Classification* CDH1 EMP1 5T4 CDH2
NT +ve +ve +ve -ve
FEP +ve/-ve +ve +ve -ve
LGD -ve -ve +ve -ve
HGD -ve -ve -ve -ve
T1 OSCC -ve -ve +ve /-ve -ve
T4 OSCC -ve -ve +ve /-ve +ve

*NT–normal tissue; A–abnormal tissue; LGD–low grade dysplasia; HGD–high grade dysplasia; T1 OSCC–T1 stage oral squamous cell carcinoma; T4 OSCC–T4 stage oral squamous cell carcinoma. CDH1 –E-cadherin; EMP–EMP1; CDH2 –N-cadherin