Table 4. Summary of marker expression in healthy, abnormal and diseased epithelium.
Classification* | CDH1 | EMP1 | 5T4 | CDH2 |
---|---|---|---|---|
NT | +ve | +ve | +ve | -ve |
FEP | +ve/-ve | +ve | +ve | -ve |
LGD | -ve | -ve | +ve | -ve |
HGD | -ve | -ve | -ve | -ve |
T1 OSCC | -ve | -ve | +ve /-ve | -ve |
T4 OSCC | -ve | -ve | +ve /-ve | +ve |
*NT–normal tissue; A–abnormal tissue; LGD–low grade dysplasia; HGD–high grade dysplasia; T1 OSCC–T1 stage oral squamous cell carcinoma; T4 OSCC–T4 stage oral squamous cell carcinoma. CDH1 –E-cadherin; EMP–EMP1; CDH2 –N-cadherin