Table 2. Upstream regulators predicted to be activated.
| Upstream Regulator | Molecule Type | z-score | p-value of overlap |
|---|---|---|---|
| Hdac | group | 2.923 | 1.03E-05 |
| SFTPA1 | transporter | 2.881 | 4.78E-06 |
| DUSP1 | phosphatase | 2.276 | 2.16E-03 |
| PLAU | peptidase | 2.168 | 1.98E-06 |
| 2-amino-5-phosphonovaleric acid | chemical—other | 2.11 | 1.87E-03 |
| Immunoglobulin | complex | 2.101 | 3.39E-04 |
| IRF3 | transcription regulator | 2.062 | 1.97E-03 |
| ZBTB20 | transcription regulator | 1.969 | 1.16E-03 |
| stallimycin | biologic drug | 1.842 | 3.51E-06 |
| bromodeoxyuridine | chemical drug | 1.838 | 8.16E-06 |
| IFNB1 | cytokine | 1.758 | 1.10E-06 |
| PPARGC1A | transcription regulator | 1.641 | 1.08E-03 |