Table 1. Socio demographic, biochemical, serological and virological profile of 57 treatment naïve acute and chronic HBV DNA positive patients enrolled in the study during June to August 2014.
| Variable | All | Acute infection | Chronic infection | p value | |
|---|---|---|---|---|---|
| % (n) | % (n) | % (n) | |||
| N = 57 | 38.5 (22) | 61.5 (35) | |||
| Age a | 32.25 (12–65) | 29.5 (19–65) | 28.0 (12–60) | 0.104 c | |
| Sex | |||||
| Male | 82.5 (47) | 90.9 (20) | 77.1 (27) | ||
| Female | 17.5 (10) | 9.1 (2) | 22.9 (8) | ||
| Biochemical (mean; min–max) | |||||
| AST(SGOT) a | 74.82 (18.0–482.0) | 101.95 (22.0–482.0) | 57.2 (18.0–319.0) | 0.01b | |
| ALT (GSPT) a | 87.69 (22.0–405.0) | 116.27 (28.0–405.0) | 69.2 (22.0–313.0) | 0.002 b | |
| Creatinin a | 73.2 (34.0–134.0) | 75.8 (48.0–134.0) | 71.4 (34.0–119.0) | 0.486 b | |
| Bilirubin a | 21.4 (2.5–189.1) | 36.2 (2.9–189.1) | 5.7 (2.5–21.0) | 0.006 b * | |
| HBV Serology | |||||
| Anti HBs | 5.3 (3) | 4.5 (1) | 5.7 (2) | 0.847 c | |
| HBe Ag | 33.3 (19) | 50.0 (11) | 22.9 (8) | 0.034 c * | |
| Anti HBe | 47.4 (27) | 36.4 (8) | 54.3 (19) | 0.187 c | |
| Anti HBc Total | 96.5 (55) | 95.5 (21) | 97.1 (34) | 0.736 c | |
| Anti HBc IgM | 38.6 (22) | 100 (22) | 0.0 (0) | 0.001 c ** | |
| Genotype (n = 53) | |||||
| A | 18.9 (10) | 13.6 (3) | 22.6 (7) | 0.422 c | |
| C | 45.3 (24) | 45.5 (10) | 45.2 (14) | 0.984 c | |
| D | 35.8 (19) | 40.9 (9) | 32.3 (10) | 0.527 c | |
| HBV viral loadc | 7.3x103 (1.1x102–4.9x108) | 2.9x106 (3.9x102–4.9x108) | 3.2x 103 (1.1x102–5.7x107) | 0.001 b** | |
a = mean (minimum–maximum)
b = Mann-Whitney U test
c = Person’s chi square test
* = <0.05
** = <0.01