Table 4. Mutations in the BCP, PC/core gene associated with HCC in 53 HBV isolates from Bangladesh.
| Variable | All | Genotype A | Genotype C | Genotype D | p value d | |
|---|---|---|---|---|---|---|
| % (no) | % (no) | % (no) | % (no) | |||
| N = 53 | n = 10 | n = 24 | n = 19 | |||
| Nucleotide | ||||||
| Mutation in BCP region | ||||||
| C1653T | 5.7 (3) | 10 (1) | 8.3 92) | 0 (0) | 0.297 | |
| T1753C | 13.2 (7) | 20 (2) | 16.7 (4) | 5.3 (1) | 0.443 | |
| G1757A | 37.7 (20) | 30 (3) | 29.2 (7) | 52.6 (10) | 0.258 | |
| A1762T | 32.1 (17) | 60 (6) | 29.2 (7) | 21.1 (4) | 0.097 | |
| G1764A | 37.7 (20) | 70 (7) | 33.3 (8) | 26.3 (5) | 0.059 | |
| A1762T/G1764A | 32.1 (17) | 60 (6) | 29.2 (7) | 21.1 (4) | 0.097 | |
| C1766G | 1.9 (1) | 0 (0) | 00.0 (0) | 5.3 (1) | 0.417 | |
| T1768A | ||||||
| Mutation in PC/Core | ||||||
| G1896A | 26.4 (14) | 0 (0) | 20.8 (5) | 47.4 (9) | 0.014* | |
| G1899A | 8.8 (5) | 0 (0) | 8.3 (2) | 15.8 (3) | 0.387 | |
| A2159G | 5.7 (3) | 0 (0) | 12.5 (3) | 0 (0) | 0.152 | |
| A2189C/T | 50.1(27) | 0 (0) | 33.3 (8) | 100 (19) | 0.000** | |
d = One way ANOVA test
* = <0.05
** = <0.01