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A dose titration of autografts treated with 0.4% CSA-TyroSpheres-gel every other day demonstrated no adverse effect on graft healing when using 0.2 ml or 0.5 ml of the TyroSpheres-gel per graft. However, when 1.0 ml of the TyroSpheres-gel was used, the autografts became macerated and sloughed by POD 12. An untreated control was performed for comparison.
