Table 4.
Initial specific to non-specific binding ratios (SNBRs), absolute annual reduction (AAR), and relative annual reduction (RAR) of the striatal subregions in the Parkinson’s disease (PD) and non-PD groups
Initial SNBR | AAR (/year) | RAR (%/year) | |||||
---|---|---|---|---|---|---|---|
Region | Side | PD | Non-PD | PD | Non-PD | PD | Non-PD |
Total striatum | Contralateral | 3.8 ± 1.2** | 6.3 ± 0.8 | 0.25 ± 0.14* | 0.10 ± 0.17 | 7.1 ± 3.6** | 1.3 ± 2.4 |
Ipsilateral | 4.2 ± 1.2** | 6.4 ± 0.8 | 0.27 ± 0.14* | 0.08 ± 0.22 | 6.7 ± 3.5** | 1.0 ± 3.2 | |
Mean | 4.0 ± 1.2** | 6.4 ± 0.8 | 0.26 ± 0.14* | 0.09 ± 0.19 | 6.9 ± 3.5** | 1.2 ± 2.7 | |
Subregion | |||||||
CA | Contralateral | 4.8 ± 1.6 | 5.6 ± 0.8 | 0.29 ± 0.20* | 0.12 ± 0.16 | 6.6 ± 4.4* | 2.0 ± 2.6 |
Ipsilateral | 5.1 ± 1.5 | 5.7 ± 0.9 | 0.26 ± 0.21 | 0.09 ± 0.22 | 5.4 ± 4.3* | 1.4 ± 3.9 | |
Mean | 5.0 ± 1.5 | 5.6 ± 0.8 | 0.28 ± 0.20* | 0.11 ± 0.18 | 6.0 ± 4.2* | 1.7 ± 3.0 | |
VS | Contralateral | 4.8 ± 1.2* | 6.1 ± 0.9 | 0.22 ± 0.19 | 0.10 ± 0.16 | 4.9 ± 3.9* | 1.5 ± 2.4 |
Ipsilateral | 5.0 ± 1.1* | 6.2 ± 0.9 | 0.21 ± 0.21* | −0.01 ± 0.20 | 4.4 ± 4.2* | −0.2 ± 3.0 | |
Mean | 4.9 ± 1.1* | 6.2 ± 0.9 | 0.22 ± 0.19* | 0.04 ± 0.16 | 4.6 ± 3.9* | 0.7 ± 2.5 | |
AP | Contralateral | 3.7 ± 1.3** | 7.2 ± 1.1 | 0.28 ± 0.14* | 0.07 ± 0.24 | 8.4 ± 4.3** | 0.8 ± 3.1 |
Ipsilateral | 4.3 ± 1.5** | 7.2 ± 1.1 | 0.33 ± 0.20* | 0.10 ± 0.27 | 8.2 ± 4.8** | 1.2 ± 3.5 | |
Mean | 4.0 ± 1.4** | 7.2 ± 1.1 | 0.31 ± 0.16* | 0.09 ± 0.24 | 8.3 ± 4.3** | 1.0 ± 3.0 | |
PP | Contralateral | 2.3 ± 1.0** | 6.7 ± 0.9 | 0.21 ± 0.13* | 0.09 ± 0.18 | 9.4 ± 4.2** | 1.1 ± 2.3 |
Ipsilateral | 2.9 ± 1.2** | 6.8 ± 0.9 | 0.27 ± 0.12* | 0.09 ± 0.23 | 9.7 ± 3.6** | 1.2 ± 3.1 | |
Mean | 2.6 ± 1.1** | 6.7 ± 0.9 | 0.24 ± 0.11* | 0.09 ± 0.20 | 9.6 ± 3.6** | 1.2 ± 2.7 |
*< 0.05, **< 0.001; CA caudate nucleus; VS ventral striatum; AP anterior putamen; PP posterior putamen