Comparison of the reproducibility of %ID determined by SPECT/CT (n = 18 individual kidneys from 9 healthy young volunteers) and planar scintigraphy (n = 24 individual kidneys). Upper panels show the SPECT/CT results at 1–2 min (a), 2–3 min (b), and 3–4 min (c) after Tc-99m DTPA injection. The %CVs of the SPECT/CT were 8.0918%, 6.5259%, and 8.8466% for 1−2 min, 2−3 min, and 3−4 min, respectively. The ICCs (95% confidence interval) of the SPECT/CT were 0.9212 (0.7893–0.9705), 0.9379 (0.8339–0.9768), and 0.8750 (0.6657–0.9532) for 1−2 min, 2−3 min, and 3−4 min, respectively. The most acceptable SPECT/CT measurement was obtained at 2–3 min post-injection, at which time point the reproducibility was better than that obtained with planar scintigraphy at 2–3 min (d) post-injection [%CV = 6.7689%, and ICC (95% CI) = 0.9368 (0.8539–0.9727)]