Table 1.
Characteristics of the volunteers and the renal tumor patients
| Volunteers (n = 19) | Renal tumor patients (n = 19) | P value (statistical test) | ||
|---|---|---|---|---|
| Young volunteers (n = 9) | Old volunteers (n = 10) | Preoperative data | ||
| Age (years) | 25.7 ± 5.9 | 59.9 ± 10.8 | 53.6 ± 13.1 | 0.0001 (Kruskal-Wallis, lowest in young volunteers) |
| Male:female ratio | 5:4 | 10:0 | 11:8 | 0.0433 (chi-square test) |
| Blood chemistry | ||||
| Serum creatinine (mg/dl) | 0.78 ± 0.15 | 1.26 ± 0.33 | 0.85 ± 0.27 | 0.001 (ANOVA, highest in old volunteers) |
| eGFRa (ml/min/1.73 m2) | 108.6 ± 10.2 | 64.3 ± 20.2 | 91.3 ± 20.3 | < 0.001 (ANOVA, lowest in old volunteers) |
| Total protein (g/dl) | 7.12 ± 0.34 | 7.29 ± 0.33 | 7.22 ± 0.52 | NS§ |
| Albumin (g/dl) | 4.51 ± 0.33 | 4.44 ± 0.17 | 4.34 ± 0.29 | NS |
| AST† (IU/l) | 20.4 ± 4.59 | 23.6 ± 6.12 | 24.7 ± 13.0 | NS |
| ALT‡ (IU/l) | 21.6 ± 14.8 | 22.6 ± 10.7 | 30.1 ± 31.3 | NS |
| Urinalysis | ||||
| Albuminuria (yes:no) | 0:9 | 2:8 | 0:19 | NS |
| Glycosuria (yes:no) | 0:9 | 0:10 | 1:18 | NS |
| Underlying diseases | ||||
| Diabetes (yes:no) | 0:9 | 3:7 | 2:17 | NS |
| Hypertension (yes:no) | 0:9 | 4:6 | 5:14 | NS |
AST aspartate aminotransferase, ALT alanine aminotransferase, NS not significant
aEstimated GFR using the abbreviated Modification of Diet in Renal Disease formula: eGFR (ml/min/1.73 m2) = 175 × sCr-1.154 × age-0.203 × (0.742 if female)