Table 1. Baseline characteristics.
Characteristics | Marfan syndrome (n=258) | No Marfan syndrome (n=6,166) | P value |
---|---|---|---|
Age (mean ± SD) | 38.2±13.2 | 63.0±14.0 | <0.001 |
Gender, female | 92 (35.7%) | 2,115 (34.3%) | 0.653 |
Race, non-white | 49 (20.2%) | 1,078 (18.7%) | 0.535 |
Type of dissection | |||
Type A dissection | 164 (63.6%) | 3,994 (64.8%) | 0.691 |
Type B dissection | 94 (36.4%) | 2,172 (35.2%) | 0.691 |
Hypertension | 103 (41.9%) | 4,809 (78.4%) | <0.001 |
Atherosclerosis | 16 (6.8%) | 1,393 (23.0%) | <0.001 |
Known aortic aneurysm | 89 (37.6%) | 909 (14.9%) | <0.001 |
Diabetes mellitus | 10 (4.3%) | 541 (8.9%) | 0.014 |
Bicuspid aortic valve | 8 (3.8%) | 169 (3.0%) | 0.527 |
Any prior cardiac surgery | 107 (44.8%) | 835 (14.2%) | <0.001 |
Aortic valve replacement | 68 (28.8%) | 218 (3.7%) | <0.001 |
Mitral valve replacement | 9 (3.8%) | 50 (0.9%) | <0.001 |
Aortic aneurysm surgery | 88 (37.4%) | 463 (7.9%) | <0.001 |
CABG | 10 (4.3%) | 286 (4.9%) | 0.705 |
Pregnancy-associated aortic dissection | 8 (3.3%) | 15 (0.3%) | <0.001 |
SD, standard deviation.