Table 1. Characteristics of the studies included in this meta-analysis.
| Studies | Study design | Sample size (n) | Age | Males | Endpoints | Follow-up duration (months) | Univariate or multivariate | Multivariate variables |
| Kitamura T, et al.[8] | R | 304 | 30 | 169 | VT/VF | 91 | U | - |
| Sieira J, et al.[9] | P | 400 | 41 | 233 | SCD + ICD Shock | 81 | U | - |
| Andorin A, et al.[13] | R | 106 | 11 | 58 | SCD + ICD Shock + VT/VF | 54 | M | Age and ICD |
| Casado-Arroyo R, et al.[11] | P | 447 | 45 | 336 | SCD + ICD Shock + VT/VF | 50 | U | - |
| Kawazoe H, et al.[12] | R | 143 | 46 | 140 | VF | 83 | U | - |
| Rivard L, et al.[10] | R | 105 | 46 | 83 | aSCD + appropriate ICD shocks | 60 | M | Max Tp-e and QRS in lead 6 |
| Conte G, et al.[16] | P | 176 | 43 | 118 | Appropriate ICD shocks | 84 | U | - |
| Dores H, et al.[15] | R | 55 | 42 | 30 | Appropriate ICD shocks | 74 | U | - |
| Maury P, et al.[14] | R | 325 | 47 | 258 | SCD + appropriate ICD shocks | 48 | M | Sp1 ST elevation, SCN5A mutation, family history of SCD, QRS duration, Max Tp-e |
| Okamura H, et al.[17] | R | 218 | 46 | 211 | SCD + appropriate ICD shocks | 78 | M | Sp1, Syncope, inducibility of VF (PES+) |
| Son MK, et al.[19] | R | 69 | 48 | 68 | Appropriate/inappropriate ICD shocks | 57 | M | Age, presence of palpitations, sVT before implantation of ICD |
| Tokioka K, et al.[18] | R | 246 | 48 | 236 | SCD + ICD Shock + VF | 45 | U | - |
| Hiraoka M, et al.[20] | P | 460 | 52 | 432 | SCD + VF | 43 | U | - |
| Daoulah A, et al.[21] | R | 25 | 32 | 25 | Appropriate ICD shocks | 41 | NA | - |
| Delise P, et al.[23] | P | 320 | 43 | 258 | SCD + VF | 40 | M | Syncope, basal type 1 ECG |
| Nishii N, et al.[22] | P | 108 | 49 | 10 | Appropriate ICD shocks | 72 | U | - |
| Probst V, et al.[25] | R | 1029 | 45 | 745 | SCD + appropriate ICD shocks | 32 | M | Symptoms at diagnosis (aSCD/asymptomatic/syncope), Sp1, age, gender, EPS |
| Richter S, et al.[24] | P | 186 | 43 | 115 | aSCD + appropriate ICD shocks + VF | 57 | U | |
| Giustetto C, et al.[27] | P | 166 | 42 | 138 | aSCD + appropriate ICD shocks + VF | 30 | U | - |
| Kamakura S, et al.[26] | R | 330 | 51 | 315 | SCD + VF | 49 | U | - |
| Benito B, et al.[28] | P | 384 | 46 | 272 | SCD + VF | 58 | M | Gender, previous AF, symptoms at diagnosis (syncope, aSCD), Sp1, EPS |
| Eckardt L, et al.[29] | R | 212 | 45 | 152 | Appropriate ICD shocks + VF | 40 | U | - |
| Brugada J, et al.[6] | P | 547 | 41 | 408 | SCD + VF | 24 | M | Gender, Sp1, syncope, EPS (inducible) |
| Priori SG, et al.[7] | P | 200 | 41 | 152 | Cardiac arrest | 34 | U | - |
AF: atrial fibrillation; aICD: appropriate implantable cardioverter defibrillator; aSCD: aborted sudden cardiac death; EPS: electrophysiological study; ICD: implantable cardioverter defibrillator; M: multivariate; NA: not available; P: prospective; R: retrospective; sVT: sustained ventricular tachycardia; U: univariate; VF: ventricular fibrillation.