Skip to main content
. 2017 Oct 26;130(23):2516–2526. doi: 10.1182/blood-2017-07-796821

Figure 2.

Figure 2.

Loss of Cks1 restores p27kipexpression in pretumor spleens of LMP2A/λ-MYC and λ-MYC mice. (A) Representative immunohistochemical analysis of spleens from 4-week-old mice stained with p27kip1 (original magnification ×40). Representative B- and T-cell areas in white pulps are shown from a total of 3 mice of each genotypes. (B) Representative immunoblots of p27kip1 and MYC expression in purified splenic B cells from 4-week-old mice. (C) P27kip1 and (D) MYC expression were normalized to Gapdh (a loading control). The statistical differences of Cks1 knockouts against their controls are indicated with thick lines. Data represent the mean ± standard deviation. **P < .01, ****P < .0001, calculated by 1-way ANOVA with post hoc multiple comparison tests.