Table 1.
Baseline participant characteristics in the entire cohort and when categorised based on baseline physical dysfunction severity
| Total cohort (n = 100) | Baseline physical dysfunction severity | |||
|---|---|---|---|---|
| Mild (n = 38) | Moderate (n = 43) | Severe (n = 19) | ||
| Age (years) | 62.4 ± 7.3 | 62.4 ± 6.8 | 62.2 ± 7.8 | 63.0 ± 7.6 |
| Women, n (%) | 52 (52%) | 20 (53%) | 22 (51%) | 10 (53%) |
| Height (m) | 1.67 ± 0.10 | 1.67 ± 0.10 | 1.68 ± 0.09 | 1.65 ± 0.11 |
| Mass (kg) | 82.7 ± 14.3 | 82.6 ± 15.2 | 84.0 ± 14.7 | 79.8 ± 11.5 |
| Body mass index (kg/m2) | 29.64 ± 4.08 | 29.67 ± 4.29 | 29.69 ± 4.08 | 29.50 ± 3.85 |
| Knee alignmenta (degrees) | 176.8 ± 3.5 | 176.6 ± 3.7 | 176.5 ± 3.4 | 177.9 ± 3.0 |
| Neuromuscular exercise: quadriceps strengthening group | 50:50 | 20:18 | 24:19 | 6:13 |
| Bilateral osteoarthritis, yes:no | 47:53 | 15:23 | 23:20 | 9:10 |
| Radiographic disease severityb | ||||
| Grade 2 | 22 (22%) | 7 (18%) | 11 (26%) | 4 (21%) |
| Grade 3 | 43 (43%) | 16 (42%) | 17 (40%) | 10 (53%) |
| Grade 4 | 35 (35%) | 15 (39%) | 15 (35%) | 5 (26%) |
| VAS average knee pain in the past week, 0–100 mmc | 54.1 ± 15.0 | 52.8 ± 15.1 | 51.3 ± 12.5 | 62.8 ± 17.7d,e |
| WOMAC physical function, 0–100c | 39.8 ± 14.1 | 26.2 ± 8.5 | 43.2 ± 4.5d | 59.3 ± 8.2d,e |
| Knee extensor strength (Nm/kg) | 1.45 ± 0.45 | 1.49 ± 0.48 | 1.50 ± 0.43 | 1.27 ± 0.39 |
| Knee flexor strength (Nm/kg) | 0.69 ± 0.22 | 0.69 ± 0.19 | 0.70 ± 0.24 | 0.64 ± 0.23 |
WOMAC Western Ontario and McMaster Universities Osteoarthritis Index, VAS visual analogue scale
aAnatomic alignment, where neutral alignment is 181° for females and 183° for males. Varus is < 181° for females and < 183 ° for males [19]
bKellgren and Lawrence grade
cHigher scores indicates greater pain/dysfunction
dSignificantly different to mild physical dysfunction (p < 0.05)
eSignificantly different to moderate physical dysfunction (p < 0.05)