Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Oct 30;1(10):1043–1057. doi: 10.1002/hep4.1115

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 The Authors. Hepatology Communications published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

PMC Copyright notice

Biliary fibrosis shows no difference between Wt and hCYP2E1 mice. Wt and hCYP2E1 mice underwent BDL for 14 days. Wt and hCYP2E1 littermates receiving sham surgery were used as the control. (A) Liver function was assessed by serum ALT and ALP for cholestatic liver injury. (B) Immunoblotting and mRNA levels of CYP2E1 in livers from sham or BDL mice. (C) Representative images of H&E and Sirius Red staining of liver sections from sham or BDL mice. (D) mRNA level of fibrogenic genes was measured in Wt and hCYP2E1 mice. The data shown are the fold change of mRNA induction compared with Wt chow mice. Abbreviations: ALP, alkaline phosphatase; H&E, hematoxylin and eosin.