Table 2.
DEMOGRAPHICS AND PREOPERATIVE CHARACTERISTICS OF RECIPIENTS CORRELATED WITH RS3761548 GENOTYPE
Variables | C/C (n = 67) | A/C+A/A (n = 35) | P Valuea |
---|---|---|---|
Gender | 0.0011a | ||
Male | 49 (73.13) | 14 (40) | |
Female | 18 (26.87) | 21 (60) | |
Age (year) | 53.62 ± 9.46 | 53.11 ± 13.39 | 0.53 |
ABO Compatibility | 0.15 | ||
Compatible | 54 (80.60) | 32 (91.43) | |
Incompatible | 13 (19.40) | 3 (8.57) | |
Original disease | 0.72 | ||
HCV | 23 (34.33) | 14 (40) | |
HBV | 16 (23.88) | 5 (14.29) | |
Autoimmune disease | 7 (10.45) | 4 (11.43) | |
Others | 21 (31.34) | 12 (34.29) | |
MELD | 18.34 ± 8.99 | 17.88 ± 7.66 | 0.71 |
Child‐Turcotte‐Pugh | 0.58 | ||
A | 5 (7.46) | 3 (8.57) | |
B | 24 (35.82) | 9 (25.71) | |
C | 38 (56.72) | 23 (65.71) | |
Donor | 0.74 | ||
Parent | 3 (4.48) | 3 (8.57) | |
Child | 38 (56.72) | 21 (60) | |
Sibling | 10(14.93) | 4 (11.43) | |
Spouse | 14 (22.90) | 7 (20) | |
Others | 2 (2.99) | 0 (0) | |
HLA total mismatches | 3.47 ± 1.60 | 3.57 ± 1.52 | 0.75 |
HLA Class I mismatch | 2.36 ± 1.18 | 2.37 ± 1.05 | 0.93 |
HLA Class II mismatch | 1.10 ± 0.66 | 1.20 ± 0.71 | 0.48 |
GRWR | 0.89 ± 0.20 | 0.91 ± 0.20 | 0.86 |
GRWR, graft‐to‐recipient weight ratio; HBV, hepatitis B virus; HCV, hepatitis C virus; LDLT, Living donor liver transplantation; MELD, model for end‐stage liver disease; SD, standard deviation.
Categorical variables are presented as number (%) while continuous variables are presented as mean ± SD.
Pearson's chi‐squared test/ Wilcoxon rank sum tests, a difference was considered significant if P‐value was < 0.05.
Typed HLA antigens: HLA‐A1, HLA‐A2, HLA‐B1, HLA‐B2, HLA‐DR1, and HLA‐DR2.