Table 1.
BASELINE CHARACTERISTICS OF 333 PATIENTS WITH HEPATOCELLULAR CARCINOMA
| Characteristic | Number (%) or Mean ± SD Unless Noted Otherwise |
|---|---|
| Age at diagnosis (years) | 61.7 ± 12.2 |
| Gender | |
| Female | 98 (29.4) |
| Male | 235 (70.6) |
| Ethnicity | |
| African American | 7 (2.1) |
| Asian | 234 (70.3) |
| Hispanic | 31 (9.3) |
| White | 61 (18.3) |
| Virology | |
| HBV | 170 (51.1) |
| HCV | 159 (47.7) |
| HBV+HCV | 4 (1.2) |
| Birthplace | |
| United States | 84 (25) |
| Non‐United States | 249 (74) |
| Albumin (g/dL) | 3.7 ± 0.7 |
| Total bilirubin (mg/dL) | 1.6 ± 2.8 |
| Alkaline phosphate (U/L) | 149.4 ± 149.8 |
| AST (U/L) | 102.3 ± 108.8 |
| ALT (U/L) | 76.2 ± 56.5 |
| Platelet (×103 mm3) | 155.1 ± 99.8 |
| AFP (ng/mL, %) | |
| No ≤ 10 | 96 (28.8) |
| No > 10 | 237 (71.2) |
| AFP median (in those > 10 ng/mL) | 191.1 |
| First quartile | 42.5 |
| Second quartile | 1,064.3 |
| Minimum | 10.4 |
| Maximum | 1,800,000 |
| Diabetes | |
| No | 265 (79.6) |
| Yes | 50 (15) |
| Missing | 18 (5.4) |
| Family history of HCC | |
| No | 263 (80) |
| Yes | 51 (15.3) |
| Missing | 19 (5.7) |
| Cirrhosis | |
| No | 71 (21.3) |
| Yes | 257 (77.2) |
| Missing | 5 (1.5) |
| Child‐Pugh score (no. 257, %) | |
| A | 183 (71.2) |
| B | 59 (22.9) |
| C | 15 (5.8) |
| Milan | |
| Beyond | 143 (42.9) |
| Within | 190 (57.1) |
| UCSF | |
| Beyond | 110 (33) |
| Within | 223 (67) |
| Diffuse* | |
| No | 267 (80.2) |
| Yes | 66 (19.8) |
| Macrovascular invasion | |
| No | 267 (80.2) |
| Yes | 33 (9.9) |
| Missing | 33 (9.9) |
| Metastasis to lunga | |
| No | 229 (68.7) |
| Yes | 22 (6.6) |
| Missing | 82 (24.6) |
| Metastasis to bonea | |
| No | 230 (69) |
| Yes | 21 (6.4) |
| Missing | 82 (24.6) |
Diffuse tumors: multifocal or single tumor >10 cm diameter.
a
2 patients presented with both bone and lung metastasis
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; HBV, hepatitis B virus DNA; HCV, hepatitis C virus RNA.