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. 2017 Mar 27;1(3):215–229. doi: 10.1002/hep4.1026

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© 2017 The Authors. Hepatology Communications published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Reduced survival after partial hepatectomy in CCl₄‐treated Jagged1 cKO mice. Control (solid lines) and Jagged1 cKO mice (dotted lines) either untreated (blue) or treated with repeated CCl₄ injections (black) were subjected to 70% PHx. Survival rates were compared between control and Jagged1 cKO mice (five mice: three males, two females) in each untreated group and seven animals (three males, four females) in each CCl₄‐treated group. An asterisk indicates that the survival rate of CCl₄‐treated Jag1 cKO mice was significantly lower than that in the CCl₄‐treated control animals (P < 0.05). Abbreviation: PHx, partial hepatectomy.