Table 2.
CLINICAL AND PATHOLOGIC ATTRIBUTES OF THE AFRICAN AND CAUCASIAN COHORTS
| Parameter | African Cohort | Caucasian Cohort | P Value |
|---|---|---|---|
| Males (number, % of cohort)a | 56 (62) | 196 (59) | 0.606 |
| Deceased (number, % yes)a | 16 (18) | 43 (13) | 0.246 |
| Age at first biopsy (mean, range)b | 51 (34–74) | 47 (20–76) | <0.001 |
| Age at biopsy with highest Ishak fibrosis score (mean, range)b | 53 (36–74) | 49 (20–76) | 0.002 |
| Ishak fibrosis score, first biopsy (median)c | 3 | 2 | 0.016 |
| Ishak fibrosis score, highest achieved over treatment period (median)c | 3 | 2 | 0.040 |
| Periportal inflammation, first biopsy (median)c | 3 | 3 | 0.799 |
| Lobular inflammation, first biopsy (median)c | 4 | 4 | 0.269 |
| Portal inflammation, first biopsy (median)c | 1 | 1 | 0.520 |
| Total inflammation, first biopsy (median)c | 8 | 8 | 0.871 |
a
Pearson's chi square test;
b
Two‐sample Student t test, two‐tailed, pooled variances;
c
Mann‐Whitney U test.