Table 2.
CHARACTERISTICS OF THE RESPECTIVE GROUPS IN RATS FED THE CSAA‐ OR CDAA‐DIET
| CSAA (G6) | CDAA (G7) | INT747 (G8) | LO (G9) | INT747+LO (G10) | |
|---|---|---|---|---|---|
| Number of rats | 10 | 10 | 10 | 10 | 10 |
| Body weight, g | 317.8 ± 4.2 | 261.8 ± 14.5* | 238.0 ± 17.3*† | 231.2 ± 15.3*† | 207.6 ± 25.1*† |
| Liver/body weight ratio, g/100g BW | 3.3 ± 0.0 | 4.5 ± 0.5* | 4.8 ± 0.2* | 4.7 ± 0.4* | 4.8 ± 0.2* |
| ALT, IU/l | 29.0 ± 7.9 | 391.4 ± 33.6* | 232.8 ± 22.6*† | 356.2 ± 29.5* | 192.3 ± 44.6*† |
| ALB, g/dL | 4.7 ± 0.3 | 4.4 ± 0.5 | 4.5 ± 0.2 | 4.7 ± 0.4 | 4.9 ± 0.2 |
| T‐Bil, mg/dL | 0.14 ± 0.03 | 0.12 ± 0.06 | 0.11 ± 0.03 | 0.11 ± 0.05 | 0.11 ± 0.03 |
| Glucose, mg/dL | 127.2 ± 17.1 | 123.6 ± 24.4 | 145 ± 27.2 | 131.2 ± 25.6 | 125.0 ± 19.5 |
| Insulin, μU/mL | 0.9 ± 0.3 | 0.7 ± 0.5 | 1.0 ± 0.5 | 1.2 ± 0.7 | 1.1 ± 0.4 |
| QUICKI | 1.1 ± 0.3 | 1.2 ± 0.4 | 1.0 ± 0.4 | 0.8 ± 0.5 | 0.9 ± 0.3 |
| TG, mg/dL | 124.0 ± 11.3 | 132.5 ± 18.1 | 136.2 ± 18.6 | 135.2 ± 17.1 | 142.2 ± 19.1 |
| NEFA, μg/L | 309 ± 32.6 | 303 ± 27.5 | 284 ± 37.6 | 296 ± 22.1 | 286 ± 36.4 |
| Portal endotoxin | 0.19 ± 0.1 | 1.15 ± 0.22* | 0.72 ± 0.27*† | 1.01 ± 0.20* | 0.63 ± 0.25*† |
Data are represented as mean ± SD. G6‐G10, Groups 6‐10. Significant compared to G6 (*P < 0.01) and G7 († P < 0.01).
Abbreviations: ALT, alanine aminotransferase; ALB, albumin; BW, body weight; LO, Losartan; NEFA, nonesterified fatty acids; QUICKI, quantitative insulin sensitivity check index; T‐Bil, total bilirubin; TG, triglyceride.