Fig. 1.
Cervical Cancer Disease Model. Disease model of cervical cancer disease is depicted. Circles correspond to the states and arrows represent the allowed transitions. HPV: Human papillomavirus; HPV: HPV infection type 16/18 and 10 most frequent non-vaccine HPV types 31/33/35/39/45/51/52/56/58/59 implicated in cervical cancer; CIN1: Cervical intraepithelial neoplasia, grade 1; CIN2/3: Cervical intraepithelial neoplasia, grade 2 and 3