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. 2017 Dec 8;36:179. doi: 10.1186/s13046-017-0648-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — PSAT1 regulated Cyclin D1 expression through GSK3β/β-catenin. a The levels of cyclin D1 mRNA were analyzed by qRT-PCR in the indicated cells. The values of the NC and Vector groups were normalized to 1. b The protein expression levels of β-catenin, total GSK-3β, p-GSK-3β (Ser9) and cyclin D1 were examined by western blotting in the indicated cells. c Western blotting was performed in conjunction with cell fractionation to analyze the nuclear translocation and expression of β-catenin in the indicated cells. **P < 0.01, ***P < 0.001, ****P < 0.0001