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. 2017 Dec 8;15:51. doi: 10.1186/s12964-017-0206-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Cellular processes and pathways dysregulated in PDB and MDB. The 15 proteins found dysregulated in our CRPC models by in vitro experiments and bioinformatic analyses (inner circle) were distributed into one or more of 18 KEGG pathways affected in cancer (middle ring). These pathways, in turn, were grouped into four core cellular processes (outer ring). DEGs and DEPs number is shown in brackets (for more details see Additional file 1: Table S6)