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. 2017 Jun 29;1(1):e000063. doi: 10.1136/bmjophth-2016-000063

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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Tissue concentrations of RO5093151 following single oral administration of 30 mg/kg RO5093151 to rabbits. Each data point reflects the mean of individual concentration of ocular tissue (from both eyes) and plasma of three animals. Results of the ocular tissues from one eye at 2-hour postdose were excluded from the analysis due to implausible high concentrations as compared with the results from the other eyes at the same time-point. Concentrations below the detection limit were set to 0 for mean calculation.