Figure 3.

Frequencies of CD11c⁺CD11b^- DCs and Langerin⁺ DCs progressively increase in the cornea of mice with dry eye disease (DED). Representative bar charts demonstrating quantitative immunohistochemistry data on the frequencies of (A) CD11b⁺CD11c⁺ DCs, (B) CD11c⁺CD11b^- DCs and (C) CD11c⁺CD207 (Langerin)⁺ DCs in the periphery and centre of cornea at baseline and on days 2, 7 and 14 after DED induction. Data are presented as the mean±SEM of three or four independent experiments involving three to four corneas per group (*p<0.05, **p<0.01, ***p<0.001).