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. 2017 Dec 8;48:86. doi: 10.1186/s13567-017-0491-9

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Amino acid sequence alignment of anti- Campylobacter nanobodies selected for their broad specificity. The structural framework regions are indicated by FR1–FR4 and the red boxes specify the CDRs. On the basis of the variation of the amino acid sequence of the CDR3, the nanobodies were divided in twelve unique groups.