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. 2017 Dec 8;48:86. doi: 10.1186/s13567-017-0491-9

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Detection of the interaction of anti- Campylobacter nanobodies and C. jejuni KC40 by immunofluorescence microscopy. The interaction was detected by (A, C, E, G) immunofluorescence microscopy and the C. jejuni cells (B, D, F, H) were visualised by bright field microscopy. A, B A nanobody specific for F4-fimbriated enterotoxigenic E. coli shows no binding with the C. jejuni cells. C, D; E, F and G, H The anti-Campylobacter nanobodies Nb22, Nb23 and Nb84 respectively, binds specifically with the C. jejuni cells.