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. 2017 Dec 8;17:118. doi: 10.1186/s12935-017-0469-8

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Expression of miR-155-5p and CTHRC1 in the para-carcinoma tissue and carcinoma tissue of HCC patients. a miR-155-5p expression was analyzed by qRT-PCR in the para-carcinoma tissue and carcinoma tissue of HCC patients. miR-155-5p was significantly down-regulated in carcinoma tissue. “p” indicates patient. *p < 0.05. b CTHRC1 mRNA expression was detected by qRT-PCR in the para-carcinoma tissue and carcinoma tissue of HCC patients. CTHRC1 was remarkably up-regulated in carcinoma tissue. *p < 0.05. c Immunohistochemical staining of CTHRC1 in the para-carcinoma tissue and carcinoma tissue of HCC patients (× 200 magnification). The red arrow represents positive staining of CTHRC1, which was mainly located in cytoplasm. d CTHRC1 protein expression was tested by WB in the para-carcinoma tissue and carcinoma tissue of HCC patients. CTHRC1 was notably elevated in carcinoma tissue. *p < 0.05