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. 2017 Dec 8;17:757. doi: 10.1186/s12879-017-2838-2

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — True and estimated VEs when only biases B1 and B2 are present. We set the risk ratio P(NFARI if healthy)/P(NFARI if frail) =0.75 and let the risk ratio R2 = P(FARI if healthy)/P(FARI if frail) vary between 0.5 to 1.0. The probabilities of vaccination are 0.8 and 0.4 for healthy and frail persons, respectively