Table 2.
Baseline Doppler Echocardiographic Data According to Presence or Absence of Clinical Events
| Variables | All Patients n=278 | No Events n=131 (47%) | Events n=147 (53%) | P Value |
|---|---|---|---|---|
| MR grade | <0.0001 | |||
| Mild | 105 (38) | 70 (53) | 35 (24) | |
| Moderate | 117 (42) | 50 (39) | 67 (46) | |
| Severe | 56 (20) | 11 (8) | 45 (31) | |
| MR effective regurgitant orifice area, cm2 | 0.35±0.19 | 0.27±0.14 | 0.43±0.19 | <0.0001 |
| MR regurgitant volume, mL | 55±27 | 45±20 | 66±29 | <0.0001 |
| MR regurgitant fraction, % | 44±12 | 40±11 | 47±13 | 0.0006 |
| LV end‐diastolic diameter, mm | 51±6 | 49±6 | 53±6 | <0.0001 |
| Indexed LV end‐diastolic diameter, mm/m2 | 29±3 | 28±3 | 30±3 | 0.002 |
| LV end‐systolic diameter, mm | 31±6 | 29±5 | 31±6 | 0.007 |
| Indexed LV end‐systolic diameter, mm/m2 | 17±3 | 17±3 | 18±4 | 0.07 |
| Forward LV stroke volume, mL | 64±16 | 66±17 | 62±15 | 0.02 |
| Indexed forward LV stroke volume, mL/m2 | 36±8 | 38±8 | 35±8 | 0.002 |
| LV cardiac output, L/min | 4.40±1.19 | 4.45±1.14 | 4.36±1.23 | 0.54 |
| LV shortening fraction, % | 41±9 | 41±8 | 41±9 | 0.93 |
| LVEF, % | ||||
| Forward LVEF (%) | 53±16 | 59±15 | 47±15 | <0.0001 |
| Total LVEF, % | 65±5 | 65±4 | 65±6 | 0.86 |
| LV global longitudinal strain, % | −21.22±2.83 | −21.26±2.44 | −21.18±3.26 | 0.86 |
| LA diameter, mm | 42±8 | 39±6 | 44±8 | <0.0001 |
| Indexed LA diameter, mm/m2 | 24±5 | 23±4 | 25±5 | <0.0001 |
| Indexed LA volume, mL/m² | 37±17 | 33±11 | 42±20 | 0.0002 |
| Trans‐tricuspid gradient, mm Hg | 30±10 | 28±9 | 31±11 | 0.006 |
LA indicates left atrial; LV, left ventricular; LVEF, left ventricular ejection fraction; MR, mitral regurgitation.