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. 2017 Oct 2;6(10):e005295. doi: 10.1161/JAHA.116.005295

Figure 7.

Figure 7

The mTOR signal has multiple effects on cardiac differentiation. Schematic model for the role of mTOR in regulating differentiation and apoptosis of hESCs and cardiomyocytes (dotted line indicates unidentified mechanisms). AMPK indicates AMP‐dependent kinase; hESC, human embryonic stem cell; mTOR, mammalian target of rapamycin; ROS, reactive oxygen species.