Table 1.
Baseline General Characteristics of the 53 065 Individuals Selected for Study
| Variables | Total Sample (N=53 065) | Years of Exposure to cumhs‐CRP | η2 | P Value | |||
|---|---|---|---|---|---|---|---|
| Nonexposed (N=29 496) | 1‐Exposed (N=14 433) | 2‐Exposed (N=6147) | 3‐Exposed (N=2989) | ||||
| Male, n (%) | 40 433 (76.2) | 22 538 (76.4) | 11 770 (77.4) | 4629 (75.3) | 2096 (70.1) | 0.001 | <0.001 |
| Age, y | 49.00±11.73 | 47.47±11.34 | 48.86±11.68 | 53.36±11.69 | 55.79±11.15 | 0.044 | <0.001 |
| Baseline SBP, mm Hg | 128.41±19.79 | 126.48±18.97 | 128.92±19.79 | 133.36±21.09 | 134.74±21.53 | 0.019 | <0.001 |
| Baseline DBP, mm Hg | 82.64±11.35 | 81.72±11.04 | 83.16±11.45 | 84.82±11.85 | 84.72±11.87 | 0.010 | <0.001 |
| BMI, kg/m2 | 25.07±3.47 | 24.63±3.13 | 25.35±3.45 | 25.92±3.64 | 26.28±3.93 | 0.024 | <0.001 |
| FPG, mmol/L | 5.39±1.54 | 5.34±1.42 | 5.43±1.55 | 5.47±1.75 | 5.52±2.01 | 0.001 | <0.001 |
| TC, mmol/L | 4.93±1.14 | 4.88±1.14 | 4.94±1.15 | 5.02±1.07 | 5.09±1.07 | 0.003 | <0.001 |
| Current smokers, n (%) | 15 841 (29.9) | 9233 (31.3) | 4519 (31.3) | 1498 (24.4) | 591 (19.8) | 0.005 | <0.001 |
| Current drinkers, n (%) | 9729 (17.5) | 5552 (18.8) | 2545 (17.6) | 865 (14.1) | 317 (10.6) | 0.003 | <0.001 |
| Physical activity, n (%) | 7301 (13.8) | 4295 (14.6) | 1940 (13.4) | 761 (12.4) | 305 (10.2) | 0.001 | <0.001 |
| Hypertension, n (%) | 20 495 (38.6) | 10 016 (34.0) | 5825 (40.4) | 3073 (50.0) | 1581 (52.9) | 0.017 | <0.001 |
| Diabetes mellitus, n (%) | 4131 (7.8) | 1598 (6.6) | 1192 (8.3) | 640 (10.4) | 341 (11.4) | 0.003 | <0.001 |
| Hyperlipidemia, n (%) | 39 937 (75.3) | 22 002 (74.6) | 11 245 (77.9) | 4565 (74.3) | 2125 (71.1) | 0.002 | <0.001 |
| Antihypertensive medication, n (%) | 9364 (45.7) | 4313 (43.1) | 2681 (46.0) | 1513 (49.2) | 857 (54.2) | 0.003 | <0.001 |
| Antidiabetic medication, n (%) | 2697 (65.3) | 1159 (72.5) | 759 (63.7) | 486 (75.9) | 293 (85.9) | <0.001 | <0.001 |
| Lipid‐lowering medication, n (%) | 1169 (2.9) | 543 (2.5) | 325 (2.9) | 189 (4.1) | 112 (5.3) | <0.001 | 0.157 |
Continuous variables are presented as mean±SD; categorical variables are presented as numbers or percentages. Baseline DBP, diastolic blood pressure in 2006; Baseline SBP, systolic blood pressure in 2006; BMI, body mass index; cumhs‐CRP, cumulative high‐sensitivity C‐reactive protein; FPG, fasting plasma glucose; TC, total cholesterol.