Table 4.
Main Determinant | Model 1 | Model 2 | Model 3 | ||||||
---|---|---|---|---|---|---|---|---|---|
Gestational Age | RR | 95% CI | P Value | RR | 95% CI | P Value | RR | 95% CI | P Value |
Per wk | 0.86 | 0.77–0.96 | 0.008 | 0.86 | 0.76–0.96 | 0.009 | 0.87 | 0.79–0.97 | 0.011 |
Per category | |||||||||
Early term | 1.00 | Ref. | ··· | 1.00 | Ref. | ··· | 1.00 | Ref. | ··· |
Full term | 0.66 | 0.48–0.91 | 0.010 | 0.65 | 0.47–0.89 | 0.008 | 0.71 | 0.52–0.97 | 0.032 |
Late term | 0.60 | 0.40–0.90 | 0.014 | 0.59 | 0.40–0.90 | 0.013 | 0.64 | 0.44–0.93 | 0.021 |
P value, linear trendb | 0.012 | 0.011 | 0.021 |
Model 1, adjusted for cohort, age, sex, age×sex, and birth weight Z scores; model 2, model 1 plus adjustments for socioeconomic status, maternal age at child's birth, delivery mode, breastfeeding, maternal body mass index, and maternal smoking history; model 3, model 2 plus adjustment for height, maturity level, and total body fatness (sum of 4 skinfolds). Ref. indicates reference; RR, incident risk ratio of poor cardiorespiratory fitness through adolescence to young adulthood per week increase in gestational age or between individuals who were born full (n=533) or late term (n=148) vs early term (n=110); CRF indicates cardiorespiratory fitness.
Defined on the basis of the following age‐ and sex‐specific cut points for maximal oxygen uptake (in mL/kg per minute): <41.8 (childhood and adolescence) and <33 (young adulthood) in males and <34.6 (childhood and adolescence) and <24 (young adulthood) in females.
Mean gestational ages per gestational age category were 37.7 weeks (early term), 39.7 weeks (full term), and 41.1 weeks (late term).