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. 2017 Sep 27;6(10):e006467. doi: 10.1161/JAHA.117.006467

Table 4.

Associations Between Gestational Age and Incidence of Poor CRF Through Adolescence to Young Adulthood (N=791)a

Main Determinant Model 1 Model 2 Model 3
Gestational Age RR 95% CI P Value RR 95% CI P Value RR 95% CI P Value
Per wk 0.86 0.77–0.96 0.008 0.86 0.76–0.96 0.009 0.87 0.79–0.97 0.011
Per category
Early term 1.00 Ref. ··· 1.00 Ref. ··· 1.00 Ref. ···
Full term 0.66 0.48–0.91 0.010 0.65 0.47–0.89 0.008 0.71 0.52–0.97 0.032
Late term 0.60 0.40–0.90 0.014 0.59 0.40–0.90 0.013 0.64 0.44–0.93 0.021
P value, linear trendb 0.012 0.011 0.021

Model 1, adjusted for cohort, age, sex, age×sex, and birth weight Z scores; model 2, model 1 plus adjustments for socioeconomic status, maternal age at child's birth, delivery mode, breastfeeding, maternal body mass index, and maternal smoking history; model 3, model 2 plus adjustment for height, maturity level, and total body fatness (sum of 4 skinfolds). Ref. indicates reference; RR, incident risk ratio of poor cardiorespiratory fitness through adolescence to young adulthood per week increase in gestational age or between individuals who were born full (n=533) or late term (n=148) vs early term (n=110); CRF indicates cardiorespiratory fitness.

a

Defined on the basis of the following age‐ and sex‐specific cut points for maximal oxygen uptake (in mL/kg per minute): <41.8 (childhood and adolescence) and <33 (young adulthood) in males and <34.6 (childhood and adolescence) and <24 (young adulthood) in females.

b

Mean gestational ages per gestational age category were 37.7 weeks (early term), 39.7 weeks (full term), and 41.1 weeks (late term).