Table 2.
Arterial Function Measures at Baseline and Follow‐up (Adjusted for Age, Sex, and Ethnicity) by Treatment Group in the Total Sample (N=517)
| Variable | Mean (SD) | Change From Baseline, Vitamin D Minus Placebo | ||||
|---|---|---|---|---|---|---|
| Vitamin D Group (n=256) | Placebo Group (n=261) | |||||
| Baseline | Follow‐up | Baseline | Follow‐up | Mean (95% CI) | P Value | |
| Pulse rate, beats/min | 63.0 (10.0) | 65.7 (9.5) | 63.9 (11.0) | 65.7 (11.8) | 0.9 (−0.7 to 2.6) | 0.27 |
| Brachial SBP, mm Hg | 137.7 (18.4) | 128.9 (16.1) | 137.7 (16.8) | 131.0 (18.9) | −2.1 (−5.2 to 0.9) | 0.17 |
| Brachial DBP, mm Hg | 78.4 (10.6) | 73.7 (9.9) | 78.7 (9.7) | 74.8 (9.9) | −0.8 (−2.5 to 0.8) | 0.32 |
| Aortic SBP, mm Hg | 140.1 (18.4) | 131.1 (16.2) | 139.7 (17.8) | 132.9 (20.2) | −2.2 (−5.4 to 0.9) | 0.17 |
| Aortic DBP, mm Hg | 72.0 (6.6) | 69.5 (6.1) | 72.2 (6.0) | 70.2 (6.1) | −0.5 (−1.5 to 0.6) | 0.41 |
| Augmentation index, % | 30.0 (12.1) | 27.0 (11.2) | 29.9 (13.1) | 26.8 (12.6) | 0.0 (−2.4 to 2.5) | 0.98 |
| Pulse wave velocity, m/s | 9.3 (1.7) | 9.2 (1.6) | 9.3 (1.7) | 9.3 (1.9) | −0.1 (−0.2 to 0.0) | 0.18 |
| Peak reservoir pressure, mm Hg | 124.3 (17.8) | 116.5 (15.1) | 124.2 (16.4) | 118.4 (18.5) | −2.0 (−5.1 to 1.1) | 0.21 |
| Peak excess pressure, mm Hg | 28.5 (8.3) | 25.8 (7.9) | 28.1 (8.5) | 26.1 (8.3) | −0.7 (−2.5 to 1.0) | 0.40 |
| Reservoir pressure integral, mm Hg/s | 92.1 (18.3) | 83.0 (16.7) | 91.7 (21.0) | 85.4 (21.5) | −2.8 (−6.1 to 0.5) | 0.10 |
| Loge(excess pressure integral, mm Hg/s) | 1.57 (0.38) | 1.40 (0.42) | 1.54 (0.43) | 1.39 (0.43) | −0.02 (−0.11 to 0.06) | 0.59 |
| Backward pressure amplitude, mm Hg | 28.6 (7.3) | 25.3 (6.3) | 28.5 (7.5) | 25.9 (8.3) | −0.8 (−2.0 to 0.5) | 0.25 |
| Forward pressure amplitude, mm Hg | 40.0 (8.4) | 36.8 (7.9) | 39.5 (8.5) | 37.5 (9.6) | −1.2 (−2.7 to 0.4) | 0.14 |
| Loge(wave reflection index), ×10−2 | −120.6 (35.0) | −124.5 (28.8) | −118.1 (35.9) | −125.7 (35.7) | 3.7 (−4.3 to 11.8) | 0.36 |
CI indicates confidence interval; DBP, diastolic blood pressure; SBP, systolic blood pressure.