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. 2017 Oct 17;6(10):e007064. doi: 10.1161/JAHA.117.007064

Table 3.

Mean Lipids, Resting Blood Pressure, and Reynolds Risk Score According to Quartiles of Physical Activity (N=4832)

Alla Physical Activity Quartile (Min/d) Trend, P Value
1 (Low) 2 3 4 (High)
Total cholesterol (mmol/L) 197.6±39.6
Low light PA (median) 133.5 171.9 203.1 247.2
Model 1 196.2±1.2 196.8±1.1 197.9±1.1 199.4±1.2 0.05
Model 2 197.5±1.2 196.8±1.1 197.5±1.1 198.4±1.2 0.54
High light PA (median) 59.8 85.5 107.9 139.9
Model 1 194.5±1.2 197.5±1.1 196.2±1.1 201.9±1.2 <0.001
Model 2 196.8±1.2 197.9±1.1 195.6±1.1 199.9±1.2 0.24
MVPA (median) 15.9 34.7 55.5 92.3
Model 1 193.8±1.2 194.5±1.1 199.4±1.1 202.5±1.2 <0.001
Model 2 194.6±1.2 195.3±1.1 199.3±1.1 201.1±1.2 <0.001
LDL‐C (mg/dL) 115.5±34.5
Low light PA
Model 1 115.0±1.0 114.3±0.9 115.8±0.9 116.7±1.0 0.17
Model 2 115.8±1.0 114.4±0.9 115.6±0.9 116.1±1.0 0.68
High light PA
Model 1 113.8±1.0 115.8±0.9 114.2±0.9 118.1±1.0 0.02
Model 2 115.2±1.1 115.9±0.9 113.8±0.9 116.8±1.1 0.64
MVPA
Model 1 112.5±1.1 113.1±0.9 117.1±0.9 119.1±1.0 <0.001
Model 2 112.9±1.1 113.5±0.9 117.1±0.9 118.3±1.1 <0.001
HDL‐C (mg/dL) 60.4±14.5
Low light PA
Model 1 56.5±0.4 60.8±0.4 61.4±0.4 63.2±0.4 <0.001
Model 2 57.4±0.4 60.8±0.4 61.1±0.4 62.5±0.4 <0.001
High light PA
Model 1 57.2±0.4 59.5±0.4 60.8±0.4 64.2±0.4 <0.001
Model 2 58.9±0.4 59.8±0.4 60.4±0.4 62.8±0.4 <0.001
MVPA
Model 1 58.6±0.5 59.2±0.4 60.9±0.4 63.1±0.4 <0.001
Model 2 54.2±0.4 59.7±0.4 60.8±0.4 62.0±0.4 <0.001
Triglyceride (mg/dL) 109.2±56.9
Low light PA
Model 1 124.7±1.7 108.9±1.6 104.7±1.6 98.4±1.7 <0.001
Model 2 122.7±1.7 108.8±1.6 105.3±1.6 99.9±1.7 <0.001
High light PA
Model 1 118.3±1.7 111.9±1.6 107.1±1.6 99.3±1.8 <0.001
Model 2 114.5±1.8 111.4±1.6 108.2±1.6 102.6±1.7 <0.001
MVPA
Model 1 115.1±1.8 112.4±1.6 107.2±1.6 102.0±1.7 <0.001
Model 2 113.7±1.8 111.1±1.6 107.3±1.6 104.6±1.7 <0.001
Systolic BP (mm Hg) 125.7±14.2
Low light PA
Model 1 126.8±0.4 125.9±0.4 125.3±0.4 124.9±0.4 <0.001
Model 2 126.1±0.4 125.9±0.4 125.5±0.4 125.4±0.4 0.16
High light PA
Model 1 127.5±0.4 125.9±0.4 125.0±0.4 124.5±0.4 <0.001
Model 2 126.2±0.4 125.7±0.4 125.4±0.4 125.5±0.4 0.24
MVPA
Model 1 126.9±0.4 126.8±0.4 125.6±0.4 123.9±0.4 <0.001
Model 2 126.6±0.4 125.9±0.4 125.6±0.4 124.6±0.4 0.003
Diastolic BP (mm Hg) 72.4±8.7
Low light PA
Model 1 73.4±0.3 72.3±0.3 72.3±0.3 71.3±0.3 <0.001
Model 2 73.1±0.3 72.3±0.3 72.4±0.3 71.6±0.3 <0.001
High light PA
Model 1 73.2±0.3 72.6±0.3 72.3±0.3 71.4±0.3 <0.001
Model 2 72.6±0.3 72.5±0.3 72.4±0.2 71.9±0.3 0.13
MVPA
Model 1 72.7±0.3 72.6±0.3 72.4±0.2 71.8±0.2 0.02
Model 2 72.5±0.3 72.4±0.3 72.4±0.3 72.2±0.3 0.45
Reynolds Risk Score 12.7±11.0
Low light PA
Model 1 14.5±0.3 12.7±0.3 12.0±0.3 11.6±0.3 <0.001
Model 2 13.9±0.3 12.6±0.3 12.2±0.3 11.9±0.3 <0.001
High light PA
Model 1 15.5±0.3 12.9±0.3 11.7±0.3 10.6±0.3 <0.001
Model 2 14.7±0.3 12.8±0.3 11.9±0.3 11.4±0.3 <0.001
Moderate‐vigorous PA
Model 1 14.7±0.3 13.1±0.3 11.9±0.3 10.9±0.3 <0.001
Model 2 14.4±0.3 12.8±0.3 12.0±0.3 11.5±0.3 <0.001

Quartile range for PA (min/d): Low light PA: ≤154.0, 154.1 to 186.8, 186.9 to 219.8, ≥219.9. High light PA: ≤74.1, 74.2 to 96.5, 96.6 to 121.2, ≥121.3. Moderate‐vigorous PA: ≤25.2, 25.3 to 44.5, 44.6 to 69.8, ≥69.9. Model 1: mean±SE adjusted for accelerometer wear‐time, age, race‐ethnicity, education, smoking (except RRS model), alcohol, age at menopause, and SPPB score. Model 2: mean±SE adjusted for above plus BMI. BMI indicates body mass index; BP, blood pressure; HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol; MVPA, moderate‐to‐vigorous physical activity; PA, physical activity; SPPB, short physical performance battery.

a

Unadjusted mean±SD for overall cohort. Reynolds Risk Score, the 10‐Yr predicted probability (%) of developing CVD