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. 2017 Dec 5;12:8649–8670. doi: 10.2147/IJN.S147591

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© 2017 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Scheme 1 — Illustration of therapeutic strategy for HCC based on PDFI nanoparticles/NIR irradiation and PDFP nanoparticles by combining PTT/PDT and chemotherapy.

Abbreviations: ASGPR, asialoglycoprotein receptor; DOPE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; EPR, enhanced permeability and retention; HCC, hepatocellular carcinoma; I, intratumoral injection; II, intravenous injection; NIR, near infrared; PDFI, pullulan coated IR780-loaded DOPE/PF68 complex nanocore; PDFP, pullulan coated paclitaxel-loaded DOPE/PF68 complex nanocore; PF68, Pluronic F68; PDT, photodynamic therapy; PTT, photothermal therapy; PTX, paclitaxel; ROS, reactive oxygen species; T, temperature.